tetrahydroxyl diphenylethylene-2-o-gluco

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

EH-201 是一种低分子量的促红细胞生成素诱导剂。 EH-201 诱导星形胶质细胞和 PC12 神经元样细胞中促红细胞生成素、PPAR-γ 共激活剂 1α (PGC-1α) 和血红蛋白的表达。在 SD、Aβ 和 KA 小鼠模型中，通过被动回避测试评估，在体内，EH-201 治疗可以恢复记忆障碍。

EH-201 is a low MW inducer of erythropoietin. EH-201 induces expression of erythropoietin PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astrocytes and PC12 neuronal-like cells. In vivo EH-201 treatment restores memory impairment as assessed by the passive avoidance test in SD Aβ and KA mouse models. In the hippocampus of mice given EH-201 in their diet levels of erythropoietin PGC-1α and haemoglobin were increased. Treatment with EH-201 might be a therapeutic strategy for memory impairment in neurodegenerative disease physiological ageing or traumatic brain injury.

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EH-201

Others

Other Targets

Others

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55327-45-2

406.38

C20H22O9

>98% (HPLC)

DMSO:10 mM

OC[C@H]1O[C@@H](Oc2c(O)cc(O)cc2\C=C\c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O

(2S3R4S5S6R)-2-(24-dihydroxy-6-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-345-triol

(-20℃)

With Ice Pack

≥ 2 years