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tetrahydroxyl diphenylethylene-2-o-gluco
CAS No. 55327-45-2
tetrahydroxyl diphenylethylene-2-o-gluco ( EH-201 )
产品货号. M19812 CAS No. 55327-45-2
EH-201 是一种低分子量的促红细胞生成素诱导剂。 EH-201 诱导星形胶质细胞和 PC12 神经元样细胞中促红细胞生成素、PPAR-γ 共激活剂 1α (PGC-1α) 和血红蛋白的表达。在 SD、Aβ 和 KA 小鼠模型中，通过被动回避测试评估，在体内，EH-201 治疗可以恢复记忆障碍。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1296 | 有现货 |
|
| 10MG | ￥2025 | 有现货 |
|
| 25MG | ￥3386 | 有现货 |
|
| 50MG | ￥5046 | 有现货 |
|
| 100MG | ￥7185 | 有现货 |
|
| 500MG | ￥14418 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称tetrahydroxyl diphenylethylene-2-o-gluco
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述EH-201 是一种低分子量的促红细胞生成素诱导剂。 EH-201 诱导星形胶质细胞和 PC12 神经元样细胞中促红细胞生成素、PPAR-γ 共激活剂 1α (PGC-1α) 和血红蛋白的表达。在 SD、Aβ 和 KA 小鼠模型中，通过被动回避测试评估，在体内，EH-201 治疗可以恢复记忆障碍。
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产品描述EH-201 is a low MW inducer of erythropoietin. EH-201 induces expression of erythropoietin PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astrocytes and PC12 neuronal-like cells. In vivo EH-201 treatment restores memory impairment as assessed by the passive avoidance test in SD Aβ and KA mouse models. In the hippocampus of mice given EH-201 in their diet levels of erythropoietin PGC-1α and haemoglobin were increased. Treatment with EH-201 might be a therapeutic strategy for memory impairment in neurodegenerative disease physiological ageing or traumatic brain injury.
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体外实验——
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体内实验——
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同义词EH-201
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number55327-45-2
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分子量406.38
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分子式C20H22O9
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纯度>98% (HPLC)
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溶解度DMSO:10 mM
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SMILESOC[C@H]1O[C@@H](Oc2c(O)cc(O)cc2\C=C\c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O
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化学全称(2S3R4S5S6R)-2-(24-dihydroxy-6-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-345-triol
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Activating mitochondrial function and haemoglobin expression with EH‐201 an inducer of erythropoietin in neuronal cells reverses memory impairment[J]. British Journal of Pharmacology 2015 172(19):4741-4756.
产品手册
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